Applying Sysmex Inostics' ultra-sensitive liquid biopsy NGS technology, Plasma-Safe-SeqS, to the detection of gene mutations associated with AML MRD enables accelerated clinical development . The alliance is . Plasma-Safe-SeqS技術とは？ 2013年9月24日、個別化医療の領域への本格参入に向けて、血液中に流れるがん由来DNA(ctDNA)の遺伝子変異検出技術を有するSysmex Inostics社が新たにシスメックスの仲間となりました。 This new test, AML-MRD-SEQ, adds to the portfolio of ultra-sensitive Plasma-Safe-SeqS technology NGS tests available through Sysmex Inostics' CLIA lab services . "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. We detect slight amounts of original gene mutation to implement a liquid biopsy, and realize personalized medicine by contributing proper diagnostics and .
"The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. July 2, 2021. QIAGEN N.V. (Venlo, Netherlands) and Sysmex Corporation (Kobe, Japan) have entered into a global strategic alliance for the development and commercialization of cancer companion diagnostics, which will leverage both QIAGEN's leadership in this field and Sysmex's Plasma-Safe-SeqS technology for next generation sequencing (NGS). Terms of the agreement were not disclosed. 'The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity.
The AP news staff was not involved in its creation. Results: Collection of whole blood from healthy individuals in cfDNA BCTs and storage for up to 5 days at room temperature did not affect the DNA yield and . The alliance is . We believe that QIAGEN is the best for Sysmex to expand this globally," said Hiroshi Kanda, Member of the Managing Board and Senior Executive Officer, Head . In July 2021, Sysmex Corporation announced a global strategic alliance with QIAGEN to provide custom cancer companion diagnostics (CDx) utilizing Plasma-Safe-SeqS technology. Analysis of plasma cell-free DNA by ultradeep sequencing in patients with stages I to III colorectal cancer. PSS technology differentiates gene mutations from reading errors by tagging amplified DNA. This rapid portable test is designed to address the high . AML-MRD-SEQ adds to Sysmex's growing Safe-SeqS assay . This chart measures the mutant allele frequency of SafeSEQ with OncoBEAM TM technology for ESR1, PIK3CA, AKT1, ESR1, PIK3A, and AKT1 clinical samples and shows that SafeSEQ has a 99.2 percent positive agreement out of 100 for mutant allele frequency, also known as MAF, sensitivity.. R 2 = 0.9709 This assay was applied to plasma samples of GIST patients before and after treatment with a multikinase inhibitor and mutations at known and novel sites of potential secondary resistance were identified. This assay was applied to plasma samples of GIST patients before and after treatment with regorafenib (GRID III trial) and mutations at known and novel … JAMA Oncology . QIAGEN (NYSE:QGEN; Frankfurt Prime Standard:QIA) today announced a global strategic alliance with Japan's Sysmex Corporation (Tokyo Stock Exchange, First We believe that QIAGEN is the best for Sysmex to expand this globally,' said Hiroshi Kanda, Member of the Managing Board and Senior Executive Officer, Head of . Pharmaceutical Industry Editor. We have designed a highly sensitive assay based on the Safe-SeqS technology to detect de novo mutations in the KIT gene and tested its performance. The alliance is intended to promote early clinical implementation of Sysmex Inostic's technology to expedite clinical trial timelines for pharmaceutical companies that . This technology is capable of identifying gene mutations of cancer in blood with ultra-high . QIAGEN officially confirmed a global cooperation agreement with Sysmex Corporation for the development and commercialization of cancer companion diagnostics, leveraging both QIAGEN's expertise in this field and Sysmex's Plasma-Safe-SeqS platform for next-generation sequencing (NGS). "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity.
In this study, investigators utilized Sysmex Inostics' highly sensitive plasma NGS technology based on the Safe-Sequencing System (Safe-SeqS) to confirm the results of mammography findings in . Last year, for instance, Sysmex launched the Ipsogen JAK2 DX reagent, used to diagnose certain hematopoietic tumors, through a distribution agreement with Ipsogen, which Qiagen acquired in 2011. "The alliance with Qiagen promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. The partnership will leverage Qiagen's expertise in the diagnostic field and Sysmex's Plasma-Safe-SeqS technology for next generation sequencing (NGS). Sysmex and QIAGEN form an alliance to accelerate BioPharma cancer treatment discovery and development. This new test, AML-MRD-SEQ, adds to the portfolio of ultra-sensitive Plasma-Safe-SeqS technology NGS tests available through Sysmex Inostics' CLIA lab services in Baltimore, Maryland. We believe that QIAGEN is the best for Sysmex to expand this globally," said Hiroshi Kanda, Member of the Managing Board and Senior Executive Officer, Head . QIAGEN N.V. QGEN recently entered into a global strategic alliance with a Japan-based clinical laboratory systemization and solutions provider, Sysmex Corporation. AML-MRD-SEQ adds to Sysmex's growing Safe-SeqS assay . Press release content from PR Newswire. The alliance is intended to promote early clinical implementation of Sysmex Inostic's technology to expedite clinical trial timelines for pharmaceutical companies that . This technology is capable of identifying gene mutations of cancer in blood with ultra-high . This new test, AML-MRD-SEQ, adds to the portfolio of ultra-sensitive Plasma-Safe-SeqS technology NGS tests available through Sysmex Inostics' CLIA lab services in Baltimore, Maryland. This new liquid biopsy solution is a major step in developing treatment strategies to support the fight against a devastating disease," said Shinichi Sato, CEO of Sysmex Inostics, Inc. NEW YORK - Qiagen said on Thursday that it has formed a global strategic alliance with Japan's Sysmex to develop and commercialize cancer companion diagnostics using Sysmex's Plasma-Safe-SeqS next-generation sequencing technology. In July 2021, Sysmex Corporation announced a global strategic alliance with QIAGEN to provide custom cancer companion diagnostics (CDx) utilizing Plasma-Safe-SeqS technology. We believe that QIAGEN is the best for Sysmex to expand this globally," said Hiroshi Kanda, Member of the Managing Board and Senior Executive Officer, Head of . "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. Learn . In July 2021, Sysmex Corporation announced a global strategic alliance with QIAGEN to provide custom cancer companion diagnostics (CDx) utilizing Plasma-Safe-SeqS technology. The Plasma-Safe-SeqS technology can identify cancer gene mutations from blood with high sensitivity. QIAGEN N.V. (Venlo, Netherlands) and Sysmex Corporation (Kobe, Japan) have entered into a global strategic alliance for the development and commercialization of cancer companion diagnostics, which will leverage both QIAGEN's leadership in this field and Sysmex's Plasma-Safe-SeqS technology for next generation sequencing (NGS). Published by : BioBuzz Media. The isolated cfDNA was analyzed for overall DNA yield of short and long DNA fragments using qPCR as well as for mutational changes using BEAMing and Plasma Safe-Sequencing (Safe-SeqS). SafeSEQ sensitivity has 99.2% agreement with OncoBEAM TM. The two companies intend to collaborate with . For Sysmex, the latest alliance is expected to expand its Plasma-Safe-SeqS technology worldwide. Global strategic alliance to leverage Sysmex's Plasma-Safe-SeqS technology QIAGEN will use ultra-sensitive liquid biopsy applications in oncology Alliance boosts QIAGEN's co-development of companion diagnostics with drug makers QIAGEN expects significant benefits for pharma companies and cancer patients worldwide HILDEN, Germany . "The alliance with Qiagen promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. We believe that QIAGEN is the best for Sysmex to expand this globally," said Hiroshi Kanda, member of the managing board and senior executive officer, head . In total, 553 bases were analyzed per sample (171 As (31%), 105 Cs (19%), 110 Gs (20%) and 167 Ts (30%)). This technology is capable of identifying gene mutations of cancer in blood with ultra-high . The alliance is intended to promote early clinical implementation of Sysmex Inostic's technology to expedite clinical trial timelines for pharmaceutical companies that . Safe-Sequencing System (Safe-SeqS) is a highly sensitive and reliable NGS library preparation technique used in our hands to detect mutations in circulating cell free DNA of a liquid biopsy. In July 2021, Sysmex Corporation announced a global strategic alliance with QIAGEN to provide custom cancer companion diagnostics (CDx) utilizing Plasma-Safe-SeqS technology. Last year, for instance, Sysmex launched the Ipsogen JAK2 DX reagent, used to diagnose certain hematopoietic tumors, through a distribution agreement with Ipsogen, which Qiagen acquired in 2011. Previous . Qiagen has entered an international strategic alliance with Japan's Sysmex to develop and market cancer companion diagnostics (CDx) leveraging the latter's Plasma-Safe-SeqS technology for next-generation sequencing (NGS). Reinert T, Henriksen TV, Christensen E, et al. We have designed a highly sensitive assay based on the Safe-SeqS technology to detect de novo mutations in the KIT gene and tested its performance. §: 1 event detected for K 2 EDTA 2 h C>G; #: 0 events . "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. Sysmex Corporation (Börse Tokio, erster Handelsabschnitt [Ticker-Code: 6869]) bekannt gegeben. The Safe-SeqS technology is in development at Sysmex Inostics. July 5, 2021. QIAGEN Forms Strategic Alliance With Sysmex Corporation for Global Cancer Companion Diagnostics Development and Commercialization Using NGS and Plasma-Safe-SeqS Technology * Global strategic . We believe that QIAGEN is the best for Sysmex to expand this globally," said Hiroshi Kanda, Member of the Managing Board and Senior Executive Officer, Head . Combining QIAGEN's global reach with Sysmex Inostic's ultra-sensitive liquid biopsy, Plasma-Safe-SeqS, capabilities is an important milestone in advancing the use of NGS technologies in clinical decision-making. QIAGEN N.V.: QIAGEN Forms Strategic Alliance With Sysmex Corporation for Global Cancer Companion Diagnostics Development and Commercialization Using NGS and Plasma-Safe-SeqS Technology Abstract. OncoBEAM is a product of Sysmex Inostics and is based on the BEAMing technology. July 2, 2021. "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. QIAGEN's (QGEN) new campus is expected to bring the benefits of transformational molecular diagnostics to Manchester and the global healthcare market. Ziel ist die Entwicklung und Vermarktung von Begleitdiagnostika für Krebserkrankungen, die die führende Expertise von QIAGEN in diesem Bereich sowie die von Sysmex entwickelte Plasma-Safe-SeqS- Sysmex Corporation has a strategic alliance with QIAGEN N.V. for the development and commercialization of cancer companion diagnostics using Plasma-Safe-SeqS technology. In July 2021, Sysmex Corporation announced a global strategic alliance with QIAGEN to provide custom cancer companion diagnostics (CDx) utilizing Plasma-Safe-SeqS technology. For Sysmex, the latest alliance is expected to expand its Plasma-Safe-SeqS technology worldwide. (B) Safe-SeqS was applied to analyze base changes in five c-KIT amplicons from healthy donor blood samples stored in K 2 EDTA tubes and cfDNA BCTs at RT for the indicated time (n = 15). Qiagen has entered an international strategic alliance with Japan's Sysmex to develop and market cancer companion diagnostics (CDx) leveraging the latter's Plasma-Safe-SeqS technology for next-generation sequencing (NGS). "The alliance with QIAGEN promises Sysmex a great application for Sysmex's Plasma-Safe-SeqS technology, which can detect gene mutations of cancer in blood with ultra-high sensitivity. Results: Collection of whole blood from healthy individuals in cfDNA BCTs and storage for up to 5 days at room temperature did not affect the DNA yield and .
Plasma-Safe-SeqS: Technology for achieving high sensitivity in next-generation sequencer by tagging genes 1) Gene Measurement Platform Overview of Gene Testing Technology Required detection sensitivity (mutation rate) 10% 1% 0.1% 0.001%0.01% Specimen (tissue biopsy) PCR Digital PCR Platforms Samples BEAMing Plasma-Safe-SeqS Clinical PCR Next . July 2, 2021. QIAGEN (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced a global strategic alliance with . Published on : July 1, 2021. Qiagen has entered into a global strategic alliance with Japanese firm Sysmex to develop and commercialise cancer companion diagnostic products. For Sysmex, the latest alliance is expected to expand its Plasma-Safe-SeqS technology worldwide. Applying Sysmex Inostics' ultra-sensitive liquid biopsy NGS technology, Plasma-Safe-SeqS, to the detection of gene mutations associated with AML MRD enables accelerated clinical development . The two companies have a longstanding relationship in developing cancer companion diagnostics.
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